Double [3 + 2] cycloadditions for diastereoselective synthesis of spirooxindole pyrrolizidines
نویسندگان
چکیده
Abstract One-pot two sequential [3 + 2] cycloadditions of azomethine ylides with different dipolarophiles for diastereoselective synthesis spirooxindole pyrrolizidines are introduced. This one-pot involving five components generates a highly condensed ring system bearing seven stereocenters diastereoselectively. The new method has high pot, atom, and step economy. Only equivalents water released as side product.
منابع مشابه
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ژورنال
عنوان ژورنال: Green Processing and Synthesis
سال: 2022
ISSN: ['2191-9542', '2191-9550']
DOI: https://doi.org/10.1515/gps-2022-0088